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To summarize:
The application of the various non-invasive techniques with different resolution, penetration depth into the skin and contrast mechanism allows a detailed, in-vivo characterization of human skin in general and of age-related changes in particularSignificant differences in thickness, location and structure of various skin layers between younger and older skin have been foundA comparison of methods allows a better interpretation of the images: A good correspondence between CLSM and OCT is obtained.
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