This schematic overview presents the mean values, as obtained by OCT and CLSM on the forearm in the two age groups. The location and thickness of the various skin layers and their changes with age are indicated. Here, I just want to focus on the values obtained in the dermis: Our measurements showed just below the epidermis a low scattering "optically dark" area. Only little contrast is obtained in the CLSM images of this first dermal layer. At a certain depth UD a highly scattering layer of fibrous structure is observed. This layer of collagen fibers is located much deeper in the dermis in younger skin as compared to older skin.With OCT a second bright reflecting layer was measured. The values of this second layer Doct and the values for UD appear to be of the same order of magnitude, suggesting that their signals might be due to the same layer in the skin.
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