Steven L. Jacques, Ph.D., Department of Electrical and Computer Engineering
Oregon Graduate Institute, Portland, Oregon, USA. email:,

The basic idea.

Human skin presents a multilayered tissue, an epidermis and underlying dermis, which presents a regular texture to the doctor. As cancer grows into the dermis, the birefringent collagen of the dermis is replaced with a less birefringent cellular mass. Our goal is to visualize this perturbation.

SKIN skin ca
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The doctor's view of surface shows cancer as a subtle perturbation. Imaging with polarized light enhances this optical perturbation.

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