@article{viator98c, author = {John A. Viator and Scott A. Prahl}, title = {Indocyanine Green Deposition in Aortic Heterograft After Photobleaching with An 800\,nm 5 Millisecond Diode Laser Pulse}, journal = {Proceedings of the Oregon Academy of Science}, volume = {34}, pages = {41--42}, year = {1998 abstract only}, abstract = {Laser tissue welding is a thermal process that causes binding of two tissue samples after irradiation by a laser pulse. The absorption of the laser energy is aided by the addition of a dye such as Indocyanine Green (ICG) on one tissue surface. ICG has an absorption peak at 774\,nm when dissolved in water, thus making an 800\,nm diode laser a suitable choice for welding. After successive laser pulses, the dye photobleaches from green to orange, altering the absorption characteristics of the dyed tissue. We measured the ICG deposition in aortic heterograft by analyzing the acoustic wave induced by irradiation of the dyed tissue by a Q-switched Nd-YAG laser. The Nd-YAG laser was coupled to an Optical Parametric Oscillator (OPO) for an output pulse of 800\,nm and 4.75\,ns. The dye deposition was analyzed for successive pulses of the diode laser until the dye was fully photobleached, indicated by an orange color. The absorption profiles obtained could be used for optimization of laser pulse parameters in laser tissue welding.}, }