@article{prahl02a,
  author = {Scott A. Prahl},
  title = {A Semi-Analytic Model for Fiber-Based Fluorescence Measurements},
  journal = {Proceedings of the Oregon Academy of Science},
  volume = {38},
  pages = {48},
  year = {2002 abstract only},
  abstract = {A semi-analytic model for a single optical fiber that delivers exitation light and collects fluoresence emission is presented. The amount of light collected by the fiber depends on the properties of the fluorophore, the characteristics of the fiber (e.g., numerical aperture, diameter) and on the optical properties of the medium at the excitation and emission wavelengths. The obvious method for estimating the fluorescent light returning to the fiber is to use a Monte Carlo model. A semi-analytic model was created to avoid long Monte Carlo simulations. A wholly empirical model was not considered because of the number of optical parameters. The semi-analytic model requires a single Monte Carlo simulation for conservative scattering to obtain the model coefficients. Absorption at the exitation and emission wavelengths is incorporated analytically into the model. The sensitivity of the model is assessed numerically and the model is validated using phantoms with known optical properties.},
}