@article{prahl01b, author = {Scott Prahl}, title = {Sized-Fiber Fluorimetry}, journal = {Proceedings of the Oregon Academy of Science}, volume = {37}, pages = {66}, year = {2001 abstract only}, abstract = {Sized-fiber fluorimetry uses two optical fibers with different diameters or numerical apertures to collect light. In vivo fluorescence measurements in tissue are confounded by the presence of scattering and non-fluorophore absorption. Sized-fiber fluorimetry makes measurements of remitted light at both the excitation and emission wavelengths (with both fibers). Experiments in scattering solutions with known fluorophore concentrations are shown to be consistent with Monte Carlo simulations. The ability of this technique to localize the measurement and to minimize the influence of other absorbers make sized-fiber fluorimetry a useful tool for fluorescence measurements in turbid materials.}, }