@article{moffitt01b, author = {Ted Moffitt and Scott Prahl}, title = {Sampling Depths of the Sized-Fiber Technique}, journal = {Proceedings of the Oregon Academy of Science}, volume = {37}, pages = {65}, year = {2001 abstract only}, abstract = {Sized-fiber array spectroscopy describes a device and method for measuring absorption and reduced scattering properties of tissue. The device consists of two fibers with different diameters that are used to measure the amount of light back-scattered into each fiber. This talk presents Monte Carlo simulations of the sized fiber device to indicate the depth that photons penetrate into tissue before being collected using 200 and 600 micron fiber sizes. Histograms of the mean photon depth are presented. Monte Carlo simulations are also presented that demonstrate the loss of diffuse reflectance collected as a function of distance to an optically thick absorbing plane embedded in highly scattering medium. The highly scattering medium has optical properties in the range of tissue. Experimental results are presented for a device with these fiber sizes to verify the sensitivity of the device to an absorbing plane layer beneath a tissue phantom. An Intralipid and india ink layer is used as the tissue model, since the absorption and reduced scattering coefficient are known.}, }