@inproceedings{janis02a,
  author = {A. D. Janis and K. W. Gregory and S. J. Kirkpatrick and S. A. Prahl},
  title = {Effects of In Vitro Target Compression Modulus on Laser Thrombolytic Ablation Rate},
  booktitle = {SPIE Proceedings on Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII},
  year = {2002},
  volume = {4609},
  pages = {419--429},
  abstract = {Laser thrombolysis (LT) is under investigation as a safe and rapid therapy for arterial recanalization in acute embolic stroke. Clot formation is a complex process affected by many factors that lead to differences in strength and hemoglobin concentration in samples formed from whole blood. The strength of thrombus formed in vivo also varies with age. Laser thrombolysis experiments were performed using a 577\,nm 1$\mu$sec pulsed dye laser at an energy of approximately 25\,mJ and a repetition rate of 4\,Hz. Laser ablation and confined compression modulus were measured with three in vitro clot models: gelatin, static clot, and reconstituted clot. Laser ablation studies demonstrate that LT ablation efficiency (in $\mu$g/mJ/pulse) is not significantly affected by differences in the confined compression modulus of clot. This agrees with previous studies using dye and gelatin. These results provide support for the effective use of this laser thrombolysis system for the removal of clots of varied age and strength.},
}