@article{dayton10c, author = {Amanda Dayton and Laurel Soot and Ronald Wolf and Christina Gougoutas-Fox and Scott A. Prahl}, title = {Light Guided Lumpectomy: Device}, journal = {J. Biomed. Opt.}, volume = {15}, number = {6}, pages = {061706}, year = {2010}, doi = {10.1117/1.3499422}, abstract = {We describe the development, design, fabrication and testing of an optical wire to assist in the surgical removal of small tumors during breast-conserving surgery. We modified a standard localization wire by adding a 200 micron optical alongside it: the resulting optical wire fit through an 18 gauge needle for insertion in the breast. The optical wire was anchored in the tumor by a radiologist under ultrasonic and mammographic guidance. At surgery, the tip was illuminated with an eye-safe, red, HeNe laser and the resulting glowball in the breast tissue surrounded the tumor. The surgeon readily visualized the glowball in the operating room. This glowball provided sufficient feedback to the surgeon that it was used to find the lesion and as a guide during tumor resection. Light guided lumpectomy was a simple enhancement to traditional wire localization that could enhance the current standard of care for small, non-palpable breast tumors.}, }