@article{chen04a,
  author = {Yin-Chu Chen and Jennifer Brazier and Mingdi Yan and Scott A. Prahl},
  title = {Steady-State Fluorescence Anisotropy Studies Of Molecularly Imprinted Polymer Sensors},
  journal = {Proceedings of the Oregon Academy of Science},
  volume = {40},
  pages = {49},
  year = {2004 abstract only},
  abstract = {Molecularly imprinted polymers (MIPs) are used as recognition elements in biochemical sensors. In a fluorescence-based MIP sensor system, it can be difficult to distinguish the analyte fluorescence from the fluorescence of the polymer itself. We studied steady-state fluorescence anisotropy of anthracene imprinted in a polymer (polyurethane) matrix. Vertically polarized excitation light was incident on MIP films coated on silicon wafers; vertically and horizontally polarized emission was measured. We compared the fluorescence anisotropy of MIPs with imprinted molecules, MIPs with the imprinted molecules extracted, MIPs with rebound molecules, and non-imprinted control polymers. It is shown that differences in fluorescence anisotropy between the polymers and imprinted fluorescent molecules may provide a means to discriminate the fluorescence of analyte from that of the background polymer.},
}